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TSC2 gene

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Tumor, Tumor, Solid, Metastasis Trial in United States (nab-sirolimus)

Recruiting
  • Tumor
  • +20 more
  • Mobile, Alabama
  • +81 more
Jan 24, 2023

Malignant Solid Tumors Trial (Sirolimus for Injection (Albumin-bound))

Not yet recruiting
  • Malignant Solid Tumors
  • Sirolimus for Injection (Albumin-bound)
  • (no location specified)
Aug 19, 2022

Lymphangioleiomyomatosis (LAM) Trial in Boston (Celecoxib)

Completed
Has Results
  • Lymphangioleiomyomatosis (LAM)
  • Boston, Massachusetts
    Brigham and Women's Hospital
Jan 18, 2022

AML, MDS, ALL, Adult Trial in Hackensack, New York (SOC + TSC-100, SOC + TSC-101, Control)

Recruiting
  • AML
  • +2 more
  • SOC + TSC-100
  • +2 more
  • Hackensack, New Jersey
  • +1 more
Aug 11, 2022

Tuberous Sclerosis Trial in United States (Ganaxolone)

Completed
  • Tuberous Sclerosis
  • Los Angeles, California
  • +6 more
Oct 27, 2022

Tuberous Sclerosis Complex, Epilepsy Trial in United States (Sirolimus, Placebo)

Recruiting
  • Tuberous Sclerosis Complex
  • Epilepsy
  • Birmingham, Alabama
  • +7 more
Sep 2, 2022

To Evaluate the Scaling Clinical Study of AAV2-RPE65 Gene Therapy Agent (LX101) in Patients With Congenital Amaurosis (LCA)

Not yet recruiting
  • To Evaluate the Scaling Clinical Study of AAV2-RPE65 Gene Therapy Agent (LX101) in Patients With Congenital Amaurosis (LCA)
  • (no location specified)
Aug 29, 2023

Tuberous Sclerosis Complex, Epilepsy Trial in Cincinnati (TAVT-18 (sirolimus))

Active, not recruiting
  • Tuberous Sclerosis Complex
  • Epilepsy
  • TAVT-18 (sirolimus)
  • Cincinnati, Ohio
    Cincinnati Children's Hospital
Jan 10, 2022

SARS-CoV-2 (Covid19) Trial in Bucharest (Trans Sodium Crocetinate, Normal saline)

Completed
Has Results
  • SARS-CoV-2 (Covid19)
  • Trans Sodium Crocetinate
  • Normal saline
  • Bucharest, Romania
    National Institute of Infectious Diseases- Prof. Dr. Matei Balş
Apr 12, 2022

Pediatric Hearing Loss Due to OTOF, GJB2, or GJB2/GJB6 Mutations

Not yet recruiting
  • Congenital Hearing Loss Secondary to Biallelic Mutations in the Otoferlin Gene (OTOF)
  • +2 more
    • (no location specified)
    Aug 25, 2023

    Arrhythmogenic Cardiomyopathy, PKP2-ACM, PKP2-ARVC Trial (LX2020)

    Not yet recruiting
    • Arrhythmogenic Cardiomyopathy
    • +2 more
    • LX2020
    • (no location specified)
    Oct 25, 2023

    Leber Congenital Amaurosis Trial in Shanghai (HG004)

    Recruiting
    • Leber Congenital Amaurosis
    • HG004
    • Shanghai, Shanghai, China
      Xinhua Hospital affiliated with Shanghai Jiao Tong UniversitySch
    Oct 12, 2023

    Age-Related Macular Degeneration Trial in Toronto (NG101 AAV gene therapy)

    Not yet recruiting
    • Age-Related Macular Degeneration
    • NG101 AAV gene therapy
    • Toronto, Ontario, Canada
      Vitreous Retina Macula Specialists of Toronto
    Aug 2, 2023

    Leber Congenital Amaurosis Trial in Shanghai (HG004)

    Recruiting
    • Leber Congenital Amaurosis
    • HG004
    • Shanghai, Shanghai, China
      Xinhua Hospital affiliated with Shanghai Jiao Tong University Sc
    Sep 26, 2023

    Sensorineural Hearing Loss, Bilateral Trial in Philadelphia (AAVAnc80-hOTOF via Akouos Delivery Device)

    Recruiting
    • Sensorineural Hearing Loss, Bilateral
    • AAVAnc80-hOTOF via Akouos Delivery Device
    • Philadelphia, Pennsylvania
      Children's Hospital of Philadelphia
    Apr 18, 2023

    ARID1A Gene Mutation, ATM Gene Mutation, ATR Gene Mutation Trial in United States (Olaparib)

    Recruiting
    • ARID1A Gene Mutation
    • +15 more
    • Scottsdale, Arizona
    • +4 more
    Dec 13, 2022

    An Intervention to Increase Genetic Testing in Families Who May

    Recruiting
    • BRCA1 Mutation
    • +21 more
    • Intervention Arm At-risk Relative/ARR Contacts
    • +5 more
    • Basking Ridge, New Jersey
    • +7 more
    Nov 22, 2022

    Her-2 Negative Breast Cancer, HRR Gene Mutation Trial in Guangzhou (Camrelizumab, Fluzoparib, Nab-paclitaxel)

    Recruiting
    • Her-2 Negative Breast Cancer
    • HRR Gene Mutation
    • Guangzhou, Guangdong, China
      First Affiliated Hospital, Sun Yat-Sen University
    Mar 7, 2023

    LGMD2C Trial (ATA-200)

    Not yet recruiting
    • LGMD2C
    • ATA-200
    • (no location specified)
    Aug 1, 2023

    Gene Editing as a Therapeutic Approach for Rett Syndrome

    Recruiting
    • Rett Syndrome
    • Gene editing in vitro
    • Siena, Italy
      University of Siena
    Feb 13, 2023

    Cardiovascular Diseases, Cohort Studies, Genotype Trial in Vandœuvre-lès-Nancy (biological, genetic, other, behavioral,

    Not yet recruiting
    • Cardiovascular Diseases
    • +4 more
    • Blood and urine samples
    • +20 more
    • Vandœuvre-lès-Nancy, Lorraine, France
      Rossignol
    Jun 14, 2023

    (MTHFR C677T) in COVID-19patients

    Completed
    • COVID 19 Associated Coagulopathy
    • RT- PCR of 2 ml EDTA blood sample to determine MTHFR C677T genotypes
    • Cairo, Egypt
      Ain Shams University
    Jan 9, 2023

    DKI Combined With APT for Post-treatment Assessment of Ovarian

    Not yet recruiting
    • Malignant Tumor of the Ovary
    • XRCC2 Gene Mutation
    • DKI and APT
    • (no location specified)
    Nov 30, 2022

    Multiple System Atrophy Trial in Irvine, Columbus (AAV2-GDNF gene therapy, Sham (Placebo) Surgery)

    Recruiting
    • Multiple System Atrophy
    • AAV2-GDNF gene therapy
    • Sham (Placebo) Surgery
    • Irvine, California
    • +1 more
    Jan 18, 2023

    Esophageal Tumors Trial (KCNA3 and OTOP2 Gene Methylation Combined Detection Kit (Fluorescent PCR Method))

    Not yet recruiting
    • Esophageal Neoplasms
    • KCNA3 and OTOP2 Gene Methylation Combined Detection Kit (Fluorescent PCR Method)
    • (no location specified)
    Dec 25, 2022